HSG Research Studies & Clinical Trials (CURRENTLY ENROLLING)
First-HD: a Phase III clinical research trial conducted in the U.S. and Canada of an investigational drug, SD-809ER led by Dr. Samuel Frank (Boston University School of Medicine) and Dr. Claudia Testa (Virginia Commonwealth University) to evaluate its safety, tolerability and effectiveness in reducing chorea.
CREST-E: A global, multi-center, clinical trial run in collaboration with Massachusetts General Hospital investigating the effects of creatine monohydrate on the progression of Huntington disease, led by Dr. Steven Hersch.
PREDICT-HD 2.0 - Observational research study for at-risk gene positive, pre-symptomatic, and gene negative tested individuals, with headquarters at the University of Iowa, under the leadership of Dr. Jane Paulsen.
On-going HSG Research Studies & Clinical Trials (ENROLLMENT COMPLETED)
Reach2HD - A clinical research trial investigating the effects of PBT2 on invidividuals with early to mid-stage Huntington disease, led by Ray Dorsey of Johns Hopkins University and Diana Rosas of Massachusetts General Hospital.
2CARE: A multi-center, randomized, double-blind, placebo-controlled trial led by Merit Cudkowicz, Michael McDermott, and Karl Kieburtz, assesing the effects of coenzyme Q10 on inviduals with mild-to-moderate Huntington disease.
PREQUEL: A clinical trial investigating the safety and tolerability of coenzyme Q10 for individuals with pre-manifest Huntington disease, led by Dr. Christopher Ross (John Hopkins University) and co-led by Dr. Kevin Biglan (University of Rochester).